United States Patent Number 5,393,533
February 28, 1995
Assignee
Pharmaceuticals microencapsulated by vapor deposited polymers and method
Patent Abstract
A microencapsulated pharmaceutical is formed by vapor depositing a polymeric
film about an active pharmaceutical agent. The film thickness of the vapor
deposited film is controlled to provide effective controlled release of said
pharmaceutical agent subsequent to application. In a preferred embodiment
the pharmaceutical is an orally ingestible pharmaceutical formed by vapor
deposition of a poly-p-xylylene polymer about a core comprising an active
pharmaceutical agent. The pharmaceutical agent exhibits surprising controlled
release activity inspite of the extreme inertness of vapor deposited films
such as Parylene films.
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